She studied for three years at the Italia Conti stage school in London, England. Other actors that have attended Italia Conti include Richard Todd, Noël Coward, Stephen Manwaring and Martine McCutcheon. She has a brother, Damian, who is two years younger than her. Also has a half-sister, Sasha, whom she credits with getting her into modeling. She started modelling professionally at 16 and starred in her first advertising campaign for Lee Jeans. Since then she's featured in campaigns for Renault Megane, Walkers and Piz Buin. Her first media break came when she was taken an interest in by the British national tabloid newspaper The Star, who still regularly publish images of her to this day. She was then recognized by, and is often featured in, the 'lad's mags' FHM, Maxim, etc. My mum was never strict. I was allowed to go out to clubs underage, watch TV, listen to whatever music I wanted to, and that made me not rebel. I have never touched a drug in my life. Why would I? My mum used to smoke cannabis in the front room, so I was never curious about it. My mum's a cool chick and in some ways we are alike. She's a strong woman, very sharp and perceptive.
She has been consistently voted one of England's sexiest women. She was featured as #97 in Maxim magazine's "Hot 100 Women of 2002" supplement. She was ranked #1 in the 2005 FHM list of "100 Sexiest Women in the World". She was ranked #71 on Maxim's Hot 100 Women of 2005 list. In 2007, she came sixth in a Daily Star readers' poll to find the "best breasts in Britain". She was ranked #8 in the 2011 FHM list of "100 Sexiest Women in the World". She was in a relationship with Jason Statham from 1997 to 2004. She was engaged to Billy Zane, having been in a relationship with him since July 2004 (April 2005-August 2008). She was in a relationship with Danny Cipriani (September 2008-June 2010). She was in a relationship with Thom Evans (November 2010-January 2013). On 17 March 2011 she announced that she and boyfriend Thom Evans, whom she has been in a relationship with since November 2010, were expecting their first child together. On 9 May 2011 her publicist confirmed that Brook had suffered a miscarriage at five months pregnant the previous week and was now resting in her farmhouse in Kent. She became pregnant a second time by her boyfriend Thom Evans in December 2011, but she suffered another miscarriage in February 2012. She has been in a relationship with French fitness instructor Jeremy Parisi since April 2015.