After her Emmy win, Brosnahan stated that Mrs. Maisel resonated with viewers because "the show is equal parts fantasy and reality. It has beautiful clothes, beautiful sets. I think in some ways it's aspirational too. It's about a woman who's reinventing herself after completing the dream she had laid out for herself. Everything falls apart; she finds herself anew. It's never too late to do that. And it's funny and, I think, filled with joy at its core, and that's something we need a lot more of in the world right now." She was cast as the lead role and title character of the Amazon Video series, The Marvelous Mrs. Maisel, which premiered in 2017. Her performance earned her a Critics' Choice Television Award and Golden Globe Award for Best Actress, and the Primetime Emmy Award for Outstanding Lead Actress in a Comedy Series.
